A cold rain drizzled on the field as Game 2 of the World Series approached, prompting discussion of a delay or postponement. The end result was a seven-minute delay in start time and a soggy contest. With his voice unfortunately showing the wear and tear of almost 70 years, Lou Rawls performed the National Anthem prior to the game.

RF-R Jermaine Dye once again logged the first hit of the game, though this time he merely singled on a groundball knocked to left-center. 1B-R Paul Konerko struck out to end the first, so the game remained scoreless going into the second. Leading off the second, 3B-R Morgan Ensberg smacked his first pitch from LHP Mark Buehrle onto the stairs just to the right of the bullpen in left field. One out later, RF-R Jason Lane hit a grounder into left-center for a single. Lane remained at first when LF-R Chris Burke hit a flyball to Dye in right and then stole during C-R Brad Ausmus' plate appearance. Ausmus hit a soft grounder up the third baseline for a single that advanced Lane to third. The White Sox likely didn't have a play on the ball anyway, but with the wet grass and the lay of the field, it was odd to see 3B-R Joe Crede waiting for unlikely possibility that the ball would roll foul. SS-R Adam Everett struck out to send the game to the bottom of the second before Houston could build on their 1-0 lead.

One out into the bottom of the second, CF-R Aaron Rowand hit a grounder into left for a single. C-L A.J. Pierzynski then hit a flyball off the fence in left field for a single that moved Rowand to second. Burke misjudged the flight of the ball and leaped to make the catch at the wall while still over a foot to the right of its trajectory. Rowand should have been at third when the play concluded, and Pierzynski likely would have had a double, but Rowand held at first waiting to tag up as he thought Burke would make the catch. Crede hit a soft flyball down the right field line for a single that drove in Rowand and moved Pierzynski to third. SS-R Juan Uribe then hit a pop-up to shallow right field where the ball bounced off the cone of 2B-R Craig Biggio's glove. Lane picked up the ball and threw to second to retire Crede while Pierzynski crossed the plate to put Chicago up 2-1. LF-L Scott Podsednik grounded out to end the inning.

Up second in the top of the third, CF-R Willy Taveras hit a groundball into the right field corner where it bounced around long enough for his speed to earn him a triple. 1B-S Lance Berkman then hit a flyball to Rowand in center, allowing Taveras to tag up and tie the game at 2. Ensberg struck out to end the top of the inning. 2B-R Tadahito Iguchi led off the bottom of the third with a line drive single into left field. Dye advanced Iguchi to second with a broken bat groundout to first. Iguchi then moved to third when Konerko grounded out, but he remained stranded when DH-S Carl Everett became the third ground out of the inning.

Neither Buehrle nor Astros' starter LHP Andy Pettitte allowed any baserunners in the fourth. Ausmus led off the top of the fifth with a groundball hit down the third baseline for a double. Two outs later, Taveras beat out an infield grounder to short for a single that moved Ausmus to third. Up next, Berkman smacked a groundball into the left field corner for a double that drove in both Ausmus and Taveras to put Houston up 4-2. Podsednik bobbled the ball as he tried to retrieve it, so Chicago didn't even have a play on any of the runners. The Astros scoring drive came to a close with Ensberg lining out to short to end the inning.

Leading off the bottom of the fifth, Uribe also chose the left field line for a groundball double. One out later when Iguchi hit a grounder to the mound, Uribe found himself in a run down and was tagged out trying to return to second. With Dye at the plate, Pettitte picked Iguchi off first to send the game into the sixth.

Buehrle retired the side in order in the top of the sixth. With the rain continuing to fall steadily two outs into the bottom of the sixth, Carl Everett hit a line drive into left-center for a single. Up next, Rowand thumped a line drive into the left field corner for a double that moved Everett to third. The original camera angle made it appear as though the ball was a foul, but a later shot clearly demonstrated it falling fair. Ultimately, the baserunners did not lead to any runs for the White Sox as Pierzynski popped out to end the inning.

Following another one-two-three inning from Buehrle in the top of the seventh, Chris Botti performed "God Bless America" on the trumpet. RHP Dan Wheeler took the ball from Pettitte for the bottom of the seventh. One out into the bottom of the seventh, Uribe hit a flyball off the centerfield wall for a double. Wheeler struck out Podsednik but then walked Iguchi. With the count 3-2 on Dye, an inside pitch appeared to strike Dye's hands and the umpire awarded him first. However, subsequent replays demonstrated that the ball actually struck the barrel of Dye's bat. Houston Manager Phil Garner discussed the call with the home plate umpire, but the ruling stood without even an apparent appeal to first. With the bases now loaded, the Astros brought in RHP Chad Qualls to relieve Wheeler. Konerko launched Qualls' first pitch into the left field stands for a grand slam, putting Chicago back on top 6-4. The crowd was still celebrating as Carl Everett hit a groundball into right field for a single. During Rowand's at-bat, Houston caught Everett attempting to steal second, ending the inning, but the grand slam was a big momentum shift and helped motivated a cold, wet crowd.

RHP Cliff Politte took over from Buehrle prior to the eighth and pitched a one-two-three inning. A combination of Qualls and LHP Mike Gallo likewise kept the White Sox off the bases in the bottom of the eighth. Chicago closer RHP Bobby Jenks took the mound for the top of the ninth and it looked like we were going to see a replay of DH-R Jeff Bagwell's painful Game 1 plate appearance. However, Bagwell won this battle, solidly catching Jenks' sixth pitch and sending a flyball into center for a single. Lane struck out, swinging late at three consecutive pitches, but Burke took a four-pitch walk. Ausmus moved the runners to second and third when he grounded out, and Houston pinch-hit switch-hitter Jose Vizcaino for Adam Everett. Vizcaino sent a line drive into left. Bagwell scored easily and the Astros' waived Burke around third. Podsednik's throw to the plate went a few feet to the right of the line, and Burke was able to throw his body to the left avoiding the tag while sliding his hand over the plate to tie the game at 6. Vizcaino advanced to second on the throw. When Houston announced left-handed hitter Mike Lamb as the pinch-hitter for 2B-R Eric Bruntlett, Chicago removed Jenks in favor of LHP Neal Cotts. Lamb hit a flyball to Podsednik to send the game to the bottom of the ninth.

Astros' closer RHP Brad Lidge went to the mound for the Astros in the ninth as Houston sought to hold onto the tie. Uribe hit a long flyball to Taveras in center for the first out of the inning, bringing Podsednik to the plate. Podsednik set off the fireworks, catapulting the ball over the right field wall and beyond the bullpen into the stands to win the game with a walk-off home run. While Podsednik did not have any homers during the 2005 regular season, his power is not unprecedented. He displayed modest power potential in Milwaukee and many of his 2004 troubles were blamed on preoccupation with the long ball.

The White Sox head to Houston up 2-0 in the Series.